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2'-Deoxyguanosine monohydrate

2'-Deoxyguanosine monohydrate

Item no.	HY-D0185-50mg
Manufacturer	MedChem Express
CASRN	312693-72-4
Amount	50 mg
Quantity options	100 mg 10 g 10 mM/1 mL 1 g 50 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.70
Citations	[1]Ravanat JL, et al. Reaction of singlet oxygen with 2'-deoxyguanosine and DNA. Isolation and characterization of the main oxidation products. Chem Res Toxicol. 1995 Apr-May;8(3):379-88.
Smiles	O[C@H]1C[C@H](N2C=NC3=C2N=C(NC3=O)N)O[C@@H]1CO.O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	312693-72-4
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	285.26
Product Description	2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4, 8-dihydro-4-hydroxy-8-oxodG and 7, 8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer[1].
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO: 25 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Isoform	Human Endogenous Metabolite
Clinical information	No Development Reported

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HY-D0185-50mg-safety-datasheet.pdf