Comparison

N-Acetylneuraminic acid European Partner

Item no. HY-I0400-10mM
Manufacturer MedChem Express
CASRN 131-48-6
Amount 10mM/1mL
Quantity options 100 mg 10mM/1mL 1 g
Category
Type Inhibitors
Specific against other
Purity 99.90
Formula C11H19NO9
Citations [1]Kiefel MJ, et al. Synthesis and biological evaluation of N-acetylneuraminic acid-based rotavirus inhibitors[J]. J Med Chem. 1996 Mar 15;39(6):1314-20.
[2]Yoshikawa, K., et al. N-Acetylneuraminic Acid Inhibits Melanogenesis via Induction of Autophagy[J]. Cosmetics 2024, 11, 82.
[3]Zhang L, et al. Functional Metabolomics Characterizes a Key Role for N-Acetylneuraminic Acid in Coronary Artery Diseases[J]. Circulation. 2018 Mar 27;137(13):1374-1390.
[4]Yida Z, et al. High fat diet-induced inflammation and oxidative stress are attenuated by N-acetylneuraminic acid in rats[J]. J Biomed Sci. 2015 Oct 24;22:96.
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ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias NANA; Lactaminic acid
Shipping Condition Cool pack
Available
Manufacturer - Type
Natural Products
Manufacturer - Applications
COVID-19-anti-virus
Manufacturer - Targets
Endogenous Metabolite; Influenza Virus; Ras; Tyrosinase
Shipping Temperature
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Molecular Weight
309.27
Product Description
N-Acetylneuraminic acid (NANA; Lactaminic acid), a nonphenolic structure, is the predominant form of sialic from Collocalia esculenta. N-Acetylneuraminic acid plays a biological role in myocardial injury, melanoma and viral or bacterial infection. N-Acetylneuraminic acid inhibits melanogenesis by reducing tyrosinase activity and triggers myocardial injury in vitro and in vivo by activation of the Rho/Rho-associated signaling pathway through binding to RhoA and Cdc42. N-Acetylneuraminic acid may prevent high fat diet (HFD)-induced inflammation and oxidative stress, thereby prevents hyperlipidemia-associated inflammation and oxidative stress. N-Acetylneuraminic acid is promising for research in the field of melanoma, coronary artery, obesity-related diseases and hyperlipidemia[1][2][3][4][5].
Manufacturer - Research Area
Cancer; Inflammation/Immunology; Cardiovascular Disease
Solubility
H2O : ≥ 125 mg/mL
Manufacturer - Pathway
Anti-infection; GPCR/G Protein; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Clinical information
Phase 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10mM/1mL
Available: In stock
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