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Ancitabine (hydrochloride) European Partner

Item no. HY-N0093-1g
Manufacturer MedChem Express
CASRN 10212-25-6
Amount 1 g
Quantity options 10 mM/1 mL 1 g 200 mg
Category
Type Inhibitors
Specific against other
Purity 99.83
Citations [1]Aftab O, et al. Detection of cell aggregation and altered cell viability by automated label-free video microscopy: a promising alternative to endpoint viability assays in high-throughput screening. J Biomol Screen. 2015 Mar;20(3):372-81.|[2]Kirsch LE, et al. Aqueous conversion kinetics and mechanisms of ancitabine, a prodrug of the antileukemic agent cytarabine. J Pharm Sci. 1984 Jul;73(7):896-902.
Smiles OC[C@@H]1[C@@H](O)[C@H](OC2=N3)[C@H](N2C=CC3=N)O1.[H]Cl
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclo-C
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
Autophagy; CMV; DNA/RNA Synthesis
Shipping Temperature
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Molecular Weight
261.66
Product Description
Ancitabine hydrochloride is the precursor of the anticancer agent Cytarabine (HY-13605), which targets targets related to cell metabolism and proliferation. Ancitabine hydrochloride can inhibit tumor cell proliferation, interfere with the DNA synthesis process of tumor cells, and prevent cell division. Under alkaline pH conditions, Ancitabine hydrochloride can be quantitatively converted into Cytarabine and can be used in the study of cancers such as colorectal cancer[1][2].
Manufacturer - Research Area
Cancer
Solubility
DMSO: 25 mg/mL (ultrasonic)|H2O: ≥ 50 mg/mL
Manufacturer - Pathway
Anti-infection; Autophagy; Cell Cycle/DNA Damage
Clinical information
Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 g
Available: In stock
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