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Saikosaponin C

Saikosaponin C

Item no.	HY-N0249-20mg
Manufacturer	MedChem Express
CASRN	20736-08-7
Amount	20 mg
Quantity options	10 mg 1 mg 20 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.65
Citations	[1]Lee TH1, et al. A potential therapeutic effect of saikosaponin C as a novel dual-target anti-Alzheimer agent. J Neurochem. 2016 Mar;136(6):1232-1245.
Smiles	O[C@H]([C@@H](O)[C@]([H])(O[C@@H]1C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])C=C[C@@]45[C@@]2(C)C[C@H](O)[C@]6(CO5)[C@@]4([H])CC(C)(C)CC6)([H])[C@]3(C)CC1)O[C@@H]7CO[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)[C@@H]7O[C@]9([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]9O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	20736-08-7
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Amyloid-β
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	927.12
Product Description	Saikosaponin C is a bioactive component found in radix bupleuri, targets amyloid beta and tau in Alzheimer's disease. Saikosaponin C inhibits the secretion of both Aβ1-40 and Aβ1-42, and suppresses abnormal tau phosphorylation, but shows no effect on BACE1 activity and expression[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Neuronal Signaling
Clinical information	No Development Reported

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HY-N0249-20mg-safety-datasheet.pdf