Comparison

Gentiopicroside European Partner

Item no. HY-N0494-50mg
Manufacturer MedChem Express
CASRN 20831-76-9
Amount 50 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.83
Citations [1]Deng Y, et al. In vitro inhibition and induction of human liver cytochrome P450 enzymes by gentiopicroside: potent effect on CYP2A6. Drug Metab Pharmacokinet. 2013;28(4):339-44. Epub 2013 Feb 19.|[2]Yang Y, et al. Protective effect of gentiopicroside from Gentiana macrophylla Pall. in ethanol-induced gastric mucosal injury in mice. Phytother Res. 2018 Feb;32(2):259-266.|[3]Chen F, et al. Gentiopicroside inhibits RANKL-induced osteoclastogenesis by regulating NF-κB and JNK signaling pathways. Biomed Pharmacother. 2018 Apr;100:142-146.
Smiles C=C[C@@H]([C@@H]1O[C@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])O[C@@H]2CO)C(C3=CO1)=CCOC3=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Gentiopicrin
Shipping Condition Room temperature
Available
Manufacturer - Type
Natural Products
Manufacturer - Applications
COVID-19-anti-virus
Manufacturer - Targets
Cytochrome P450; HCV
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
356.32
Product Description
Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
Manufacturer - Research Area
Inflammation/Immunology
Solubility
DMSO: 250 mg/mL (ultrasonic)|H2O: ≥ 100 mg/mL
Manufacturer - Pathway
Anti-infection; Metabolic Enzyme/Protease
Isoform
CYP2
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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