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Otophylloside B

Otophylloside B

Item no.	HY-N0582-1mg
Manufacturer	MedChem Express
CASRN	106758-54-7
Amount	1 mg
Quantity options	10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.26
Citations	[1]Li JL, et al. Bioactive C21 Steroidal Glycosides from the Roots of Cynanchum otophyllum That Suppress the Seizure-like Locomotor Activity of Zebrafish Caused by Pentylenetetrazole. J Nat Prod. 2015 Jul 24;78(7):1548-55.\|[2]Yang J, et al. Otophylloside B Protects Against Aβ Toxicity in Caenorhabditis elegans Models of Alzheimer's Disease. Nat Prod Bioprospect. 2017 Apr;7(2):207-214.\|[3]Li X, et al. Antiepileptic C21 steroids from the roots of Cynanchum otophyllum. J Asian Nat Prod Res. 2015;17(7):724-32.
Smiles	O[C@]([C@@]([C@]1([H])C2)(CC=C3[C@@]1(CC[C@H](O[C@@](O[C@H](C)[C@H]4O[C@@](O[C@H](C)[C@H]5O[C@@](O[C@H](C)[C@H]6O)([H])C[C@H]6OC)([H])C[C@@H]5OC)([H])C[C@@H]4OC)C3)C)O)(CC[C@@]7(O)C(C)=O)[C@@]7([C@@H]2OC(/C=C(C)/C(C)C)=O)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	106758-54-7
Shipping Condition	Cool pack
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Amyloid-β
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, protect from light)
Molecular Weight	923.13
Product Description	Otophylloside B, a C-21 steroidal glycoside isolated from Qingyangshen. Otophylloside B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Otophylloside B has antiepileptic activity[1][2][3].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Neuronal Signaling
Clinical information	No Development Reported

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HY-N0582-1mg-safety-datasheet.pdf