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alpha-Cyperone

alpha-Cyperone

Item no.	HY-N0710-10mg
Manufacturer	MedChem Express
CASRN	473-08-5
Amount	10 mg
Quantity options	10 mMx1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.68
Citations	[1]Jung, S. H. et al. alpha-Cyperone, isolated from the rhizomes of Cyperus rotundus, inhibits LPS-induced COX-2 expression and PGE2 production through the negative regulation of NFkappaB signalling in RAW 264.7 cells. Journal of ethnopharmacology 147, 208-214, doi:10.1016/j.jep.2013.02.034 (2013).\|[2]Azimi, A. et al. alpha-Cyperone of Cyperus rotundus is an effective candidate for reduction of inflammation by destabilization of microtubule fibers in brain. Journal of ethnopharmacology, doi:10.1016/j.jep.2016.06.058 (2016).
Smiles	O=C1C(C)=C2C[C@H](C(C)=C)CC[C@@]2(C)CC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	α-Cyperone,(+)-α-Cyperone
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	218.33
Product Description	alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 100 mg/mL (ultrasonic)\|Ethanol: 140 mg/mL (ultrasonic)\|H2O: < 0.1 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Isoform	Human Endogenous Metabolite
Clinical information	No Development Reported

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HY-N0710-10mg-safety-datasheet.pdf