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Berbamine (dihydrochloride)

Berbamine (dihydrochloride)

Item no.	HY-N0714A-500mg
Manufacturer	MedChem Express
CASRN	6078-17-7
Amount	500 mg
Quantity options	10 mM/1 mL 200 mg 500 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer
Type	Inhibitors
Specific against	other
Purity	96.62
Citations	[1]Liang Y, et al. Berbamine, a novel nuclear factor kappaB inhibitor, inhibits growth and induces apoptosis in human myeloma cells. Acta Pharmacol Sin. 2009 Dec;30(12):1659-65.\|[2]Meng Z, et al. Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca<sup>2+</sup>/calmodulin-dependent protein kinase II. Mol Cancer Ther. 2013 Oct;12(10):2067-77. Cell Stress Chaperones. 2021 Jan 6.\|J Ethnopharmacol. 2022 Dec 7;303:116025.\|J Periodontol. 2024 Jul 5.\|Patent. US20220017867A1.\|SSRN. 2025 Jan 24.\|Biomed Pharmacother. 2024 Aug 15:179:117309.\|Chemrxiv. Oct 12, 2021.\|Drug Des Devel Ther. 2022 Jan 11;16:129-141.\|Mol Pharm. 2022 Oct 21.\|Oncogene. 2025 Jan 26.\|Pharmaceuticals. 2024 Nov 25.\|PLoS Pathog. 2023 Jan 26;19(1):e1011131.
Smiles	COC1=C(OC2=CC([C@]3([H])CC(C=C4)=CC=C4O5)=C(CCN3C)C=C2OC)C([C@@]6([H])CC7=CC=C(O)C5=C7)=C(CCN6C)C=C1OC.Cl.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	6078-17-7
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Autophagy; NF-κB
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	681.65
Product Description	Berbamine dihydrochloride is an inhibitor of NF-κB activity with remarkable anti-myeloma efficacy.
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 100 mg/mL\|H2O: 25 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Autophagy; NF-κB
Isoform	NF-κB
Clinical information	Launched

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HY-N0714A-500mg-safety-datasheet.pdf