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Glucosamine (hydrochloride)

Glucosamine (hydrochloride)

Item no.	HY-N0733-10mM
Manufacturer	MedChem Express
CASRN	66-84-2
Amount	10 mM/1 mL
Quantity options	10 g 10 mM/1 mL 1 g 500 mg 50 mg 5 g
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Colorectal Cancer
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9.\|[2]Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells. Int J Oncol. 2014 May;44(5):1699-706.\|[3]Park J, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84.\|[4]Bruyère O, et al. Efficacy and safety of glucosamine sulfate in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016 Feb;45(4 Suppl):S12-7. Laurea Magistrale in Biomedical Engineering, Politecnico di Milano. 2019 Jun.\|Int Immunopharmacol. 2024 Oct 18;143(Pt 2):113427.\|Microbiome. 2019 Mar 20;7(1):43. \|Nature. 2024 Dec 18.\|Theranostics. 2021 Mar 24;11(12):5650-5674.
Smiles	O=C[C@H](N)[C@H]([C@@H]([C@@H](CO)O)O)O.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	D-(+)-Glucosamine hydrochloride,Chitosamine hydrochloride
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Autophagy; Endogenous Metabolite; HIF/HIF Prolyl-Hydroxylase; Reactive Oxygen Species (ROS)
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	215.63
Product Description	Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine hydrochloride also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].
Manufacturer - Research Area	Inflammation/Immunology; Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)\|H2O: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Isoform	Human Endogenous Metabolite; Microbial Metabolite
Clinical information	Launched

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HY-N0733-10mM-safety-datasheet.pdf