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Ginkgetin

Ginkgetin

Item no.	HY-N0889-10mg
Manufacturer	MedChem Express
CASRN	481-46-9
Amount	10 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Testicular & Prostate Cancer Bone Cancer
Type	Inhibitors
Specific against	other
Purity	99.86
Formula	C32H22O10
Citations	[1]Hu WH, et, al. Synergy of Ginkgetin and Resveratrol in Suppressing VEGF-Induced Angiogenesis: A Therapy in Treating Colorectal Cancer. Cancers (Basel). 2019 Nov 20;11(12):1828. [2]Ye ZN, et, al. Biflavone Ginkgetin, a Novel Wnt Inhibitor, Suppresses the Growth of Medulloblastoma. Nat Prod Bioprospect. 2015 Mar 29;5(2):91-97. [3]Xiong M, et, al. Ginkgetin exerts growth inhibitory and apoptotic effects on osteosarcoma cells through inhibition of STAT3 and activation of caspase-3/9. Oncol Rep. 2016 Feb;35(2):1034-40. [4]Li Q, et, al. Ginkgetin exerts anti-inflammatory effects on cerebral ischemia/reperfusion-induced injury in a rat model via the TLR4/NF-κB signaling pathway. Biosci Biotechnol Biochem. 2019 Apr;83(4):675-683. [5]Lou J, et, al. Ginkgetin induces autophagic cell death through p62/SQSTM1-mediated autolysosome formation and redox setting in non-small cell lung cancer. Oncotarget. 2017 Oct 16;8(54):93131-93148.
Smiles	OC1=CC(O)=C2C(OC(C3=CC=C(O)C=C3)=CC2=O)=C1C4=CC(C(OC5=CC(OC)=CC(O)=C56)=CC6=O)=CC=C4OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	481-46-9
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Apoptosis; Autophagy; COX; Wnt
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	566.51
Product Description	Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC50 of 5.92 μΜ[1][2][3][4][5].
Manufacturer - Research Area	Inflammation/Immunology; Cancer
Solubility	DMSO : ≥ 20.83 mg/mL
Manufacturer - Pathway	Apoptosis; Autophagy; Immunology/Inflammation; Stem Cell/Wnt
Clinical information	No Development Reported

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HY-N0889-10mg-safety-datasheet.pdf