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Dencichine

Dencichine

Item no.	HY-N1477-25mg
Manufacturer	MedChem Express
CASRN	5302-45-4
Amount	25 mg
Quantity options	10 mM/1 mL 10 mg 25 mg 5 mg
Category	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.59
Citations	[1]Eslavath RK, et al. β-N-oxalyl-L-α, β- diaminopropionic acid induces HRE expression by inhibiting HIF-prolyl hydroxylase-2 in normoxic conditions. Eur J Pharmacol. 2016 Nov 15;791:405-411.\|[2]Jie L, et al. Dencichine ameliorates kidney injury in induced type II diabetic nephropathy via the TGF-β/Smad signalling pathway. Eur J Pharmacol. 2017 Oct 5;812:196-205.
Smiles	N[C@@H](CNC(C(O)=O)=O)C(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Dencichin,ODAP
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	HIF/HIF Prolyl-Hydroxylase
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	176.13
Product Description	Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity.
Manufacturer - Research Area	Neurological Disease
Solubility	0.1 M HCl: 3.33 mg/mL (ultrasonic; warming; heat to 60°C)\|DMSO: 5 mg/mL (ultrasonic)\|H2O: 5 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-N1477-25mg-safety-datasheet.pdf