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D-Tetrahydropalmatine

D-Tetrahydropalmatine

Item no.	HY-N2003-10mg
Manufacturer	MedChem Express
CASRN	3520-14-7
Amount	10 mg
Quantity options	10 mM/1 mL 10 mg 1 mg 20 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.84
Citations	[1]Ma ZJ, et al. [Effects of different types and standard of processing vinegaron inherent constituents in rhizoma of Corydalis yanhusuo]. Zhongguo Zhong Yao Za Zhi. 2006 Mar;31(6):465-7.\|[2]Xu SX, et al. Effects of tetrahydroprotoberberines on dopamine receptor subtypes in brain. Zhongguo Yao Li Xue Bao. 1989 Mar;10(2):104-10.\|[3]Tu M, et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important rolein its hepatotoxicity. Toxicology. 2013 Sep 15;311(3):225-30.
Smiles	COC1=CC=C2C(CN3CCC4=CC(OC)=C(OC)C=C4[C@@]3([H])C2)=C1OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	3520-14-7
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Dopamine Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	355.43
Product Description	D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis[1]. D-Tetrahydropalmatine is a dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors[2]. D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor[3].
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Isoform	D1 Receptor
Clinical information	No Development Reported

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HY-N2003-10mg-safety-datasheet.pdf