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Agnuside

Agnuside

Item no.	HY-N2518-10mg
Manufacturer	MedChem Express
CASRN	11027-63-7
Amount	10 mg
Quantity options	10 mM / 1 mL 10 mg 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.90
Citations	[1]Tirpude NV, et al. Agnuside mitigates OVA-LPS induced perturbed lung homeostasis via modulating inflammatory, autophagy, apoptosis-fibrosis response and myeloid lineages in mice model of allergic asthma. Int Immunopharmacol. 2022 May;106:108579. \|[2]Le DD, et al. Iridoid derivatives from Vitex rotundifolia L. f. with their anti-inflammatory activity. Phytochemistry. 2023 Jun;210:113649.\|[3] Pillarisetti P, Myers KA. Identification and characterization of agnuside, a natural proangiogenic small molecule. Eur J Med Chem. 2018 Dec 5;160:193-206.\|[4]Zhang L, et al. Agnuside Alleviates Synovitis and Fibrosis in Knee Osteoarthritis through the Inhibition of HIF-1α and NLRP3 Inflammasome. Mediators Inflamm. 2021 Mar 16;2021:5534614.
Smiles	OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@@]1([H])O[C@H]2[C@@]3([H])[C@](C=CO2)([H])[C@H](O)C=C3COC(C4=CC=C(O)C=C4)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Agnoside
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	ASCT; Caspase; COX; HIF/HIF Prolyl-Hydroxylase; NO Synthase
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	466.44
Product Description	Agnuside is used in the study of asthma, inflammation, and angiogenic diseases. Agnuside is an orally active compound that can be extracted from Vitex negundo[1][2][3][4].
Manufacturer - Research Area	Inflammation/Immunology; Cardiovascular Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Clinical information	No Development Reported
Isoform	EP

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-N2518-10mg-safety-datasheet.pdf