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Z-Gly-Gly-Arg-AMC (acetate)

Z-Gly-Gly-Arg-AMC (acetate)

Item no.	HY-P0019A-50mg
Manufacturer	MedChem Express
CASRN	2070009-61-7
Amount	50 mg
Quantity options	10 mM/1 mL 10 mg 50 mg 5 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Purity	99.87
Citations	[1]Tarandovskiy ID, et al. Antiplatelet agents can promote two-peaked thrombin generation in platelet rich plasma: mechanism and possible applications. PLoS One. 2013;8(2):e55688.\|[2]Machlus KR, et al. Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram. Thromb Haemost. 2009 Nov;102(5):936-44.\|[3]Mothukuri GK, et al. Macrocycle synthesis strategy based on step-wise "adding and reacting" three components enables screening of large combinatorial libraries. Chem Sci. 2020 Jun 26;11(30):7858-7863. Acta Pharmacol Sin. 2024 Jun 24.\|Bioorg Chem. 2019 Nov;92:103199. \|Chem Biol Interact. 2023 Apr 18;110501.\|J Mater Chem B. 2017 Oct 14;5(38):7876-7884. \|RSC Adv. 2020, 10(7):3626-3635.\|Spectrochim Acta A Mol Biomol Spectrosc. 6 August 2021, 120250.\|Int J Biol Macromol. 2019 Aug 1;134:622-630. \|Int J Biol Macromol. 2019 Sep 15;137:261-269.\|Phytochemistry. 2019 Jun 14;165:112025.
Smiles	CC(O)=O.O=C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(NC1=CC=C(C(C)=CC(O2)=O)C2=C1)=O)=O)=O)OCC3=CC=CC=C3
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	2070009-61-7
Shipping Condition	Cool pack
Available
Manufacturer - Type	Dye Reagents
Manufacturer - Targets	Fluorescent Dye; Thrombin
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Molecular Weight	639.66
Product Description	Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm)[1][2].
Manufacturer - Research Area	Others
Solubility	DMSO: 100 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O: 20 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Others
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P0019A-50mg-safety-datasheet.pdf