TRAP-6

Item no.	HY-P0078-10mg
Manufacturer	MedChem Express
CASRN	141136-83-6
Amount	10 mg
Quantity options	10 mM/1 mL 10 mg 25 mg 5 mg
Category	Cardiovascular Research Thrombosis & Hemostasis Atherosclerosis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.84
Citations	[1]Kahn ML, et, al. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest. 1999 Mar;103(6):879-87.\|[2]Kinlough-Rathbone RL, et, al. Rabbit and rat platelets do not respond to thrombin receptor peptides that activate human platelets. Blood. 1993 Jul 1;82(1):103-6.\|[3]Chintala MS, et, al. Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats. Eur J Pharmacol. 1998 May 22;349(2-3):237-43.
Smiles	O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)[C@@H](NC([C@@H](N)CO)=O)CC1=CC=CC=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Protease Activated Receptor (PAR)
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	748.87
Product Description	TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	H2O: 25 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein
Isoform	PAR1
Clinical information	No Development Reported

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HY-P0078-10mg-safety-datasheet.pdf