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PLP (139-151)

PLP (139-151)

Item no.	HY-P0129-5mg
Manufacturer	MedChem Express
CASRN	131334-43-5
Amount	5 mg
Quantity options	10 mMx1 mL 1 mg 5 mg
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Peptides & Proteins Peptides Astrocyte Markers
Type	Peptides
Specific against	other
Purity	99.74
Citations	[1]Kuchroo VK, et al. Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology. 1991;59(5):305-12.\|[2]Sobel RA, et al. Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide ofmyelin proteolipid protein. J Neuropathol Exp Neurol. 1990 Sep;49(5):468-79.\|[3]Bebo BF Jr, et al. Male SJL mice do not relapse after induction of EAE with PLP 139-151. J Neurosci Res. 1996 Sep 15;45(6):680-9.\|[4]Coda AR, et al. In vivo imaging of CNS microglial activation/macrophage infiltration with combined [18F]DPA-714-PET and SPIO-MRI in a mouse model of relapsing remitting experimental autoimmune encephalomyelitis. Eur J Nucl Med Mol Imaging. 2021 Jan;48(1):40-52.\|[5]Turvey ME, et al. Quantitative proteome profiling of CNS-infiltrating autoreactive CD4+ cells reveals selective changes during experimental autoimmune encephalomyelitis. J Proteome Res. 2014 Aug 1;13(8):3655-70.\|[6]Zhang H, et al. Intrinsic and induced regulation of the age-associated onset of spontaneous experimental autoimmune encephalomyelitis. J Immunol. 2008 Oct 1;181(7):4638-47.
Smiles	N[C@@H](CC1=CN=CN1)C(N[C@@H](CS)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	131334-43-5
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Others
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	1537.79
Product Description	PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis (EAE).
Manufacturer - Research Area	Inflammation/Immunology
Solubility	H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Others
Clinical information	No Development Reported

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HY-P0129-5mg-safety-datasheet.pdf