DAPTA

Item no.	HY-P1034-1mg
Manufacturer	MedChem Express
CASRN	106362-34-9
Amount	1 mg
Quantity options	10 mMx1 mL 10 mg 1 mg 25 mg 5 mg
Category	Neuroscience Aging & Neurological Disorders Peptides & Proteins Cardiovascular Research Atherosclerosis Peptides
Type	Peptides
Specific against	other
Purity	99.85
Citations	[1]Pollicita M, et al. Profound anti-HIV-1 activity of DAPTA in monocytes/macrophages and inhibition of CCR5-mediated apoptosis in neuronal cells. Antivir Chem Chemother. 2007;18(5):285-95.\|[2]Polianova MT, et al. Chemokine receptor-5 (CCR5) is a receptor for the HIV entry inhibitor peptide T (DAPTA). Antiviral Res. 2005 Aug;67(2):83-92.
Smiles	OC1=CC=C(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](C)N)=O)CO)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC(N)=O)=O)C(N[C@@H]([C@@H](C)O)C(N)=O)=O)C=C1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	D-Ala-peptide T-amide,Adaptavir
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	COVID-19-anti-virus
Manufacturer - Targets	CCR; HIV
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	856.88
Product Description	DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5, and shows potent anti-HIV activities.
Manufacturer - Research Area	Infection; Endocrinology
Solubility	H2O: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; GPCR/G Protein; Immunology/Inflammation
Isoform	CCR5; HIV-1
Clinical information	Phase 2

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HY-P1034-1mg-safety-datasheet.pdf