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Tirzepatide (hydrochloride)

Tirzepatide (hydrochloride)

Item no.	HY-P1731B-10mM
Manufacturer	MedChem Express
Amount	10 mMx1 mL
Quantity options	10 mMx1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Purity	99.82
Citations	bioRxiv. 2023 Dec 7. J Am Chem Soc. 2023 Dec 13. iScience. 2024 Feb 27. [1]Fontanella RA, et al. Tirzepatide prevents neurodegeneration through multiple molecular pathways. J Transl Med. 2024 Jan 29;22(1):114. [2]Huang L, et al. Tirzepatide inhibits tumor growth in mice with diet-induced obesity. bioRxiv, 2023: 2023.06. 22.546093. [3]Guo X, et al. Tirzepatide ameliorates spatial learning and memory impairment through modulation of aberrant insulin resistance and inflammation response in diabetic rats. Front Pharmacol. 2023 Aug 28;14:1146960.
Smiles	OC[C@H](NC([C@H]1N(CCC1)C([C@H]2N(CCC2)C([C@H]3N(CCC3)C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H]4N(CCC4)C(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C(C)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(C(C)(NC([C@@H](N)CC5=CC=C(C=C5)O)=O)C)=O)CCC(O)=O)=O)=O)[C@@H](C)O)=O)CC6=CC=CC=C6)=O)[C@@H](C)O)=O)CO)=O)CC(O)=O)=O)CC7=CC=C(C=C7)O)=O)CO)=O)[C@H](CC)C)=O)C)=O)CC(C)C)=O)CC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)C)=O)CCC(N)=O)=O)CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@H](NC(CCCCCCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)=O)=O)=O)C)=O)CC8=CC=CC=C8)=O)C(C)C)=O)CCC(N)=O)=O)CC9=CNC%10=C9C=CC=C%10)=O)CC(C)C)=O)[C@H](CC)C)=O)C)=O)=O)=O)=O)CO)=O)CO)=O)=O)C)=O)=O)=O)=O)C(N)=O.[H]Cl.[x]
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LY3298176 (hydrochloride)
Available
Product Description	Tirzepatide hydrochloride (LY3298176 hydrochloride) is a glucose-dependent insulin nutritive polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor dual agonist. Tirzepatide hydrochloride has neuroprotective effects and can be used in the study of type 2 diabetes, diabetes-related neuropathy and obesity[1][2][3].
StorageTemperature	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	4813.45 (free base)
Clinical_Information	Launched
Manufacturers Research Area	Cancer; Metabolic Disease; Neurological Disease
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturers Target	GLP Receptor
Pathway	GPCR/G Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P1731B-10mM-safety-datasheet.pdf