Comparison

CHF5407 European Partner

Item no. HY-U00302-5mg
Manufacturer MedChem Express
CASRN 1004312-94-0
Amount 5 mg
Quantity options 100 mg 10 mg 1 ea 1 mg 20 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.68
Citations [1]G Villetti, et al. Bronchodilator activity of (3R)-3-[[[(3-fluorophenyl)[(3,4,5-trifluorophenyl)methyl]amino] carbonyl]oxy]-1-[2-oxo-2-(2-thienyl)ethyl]-1-azoniabicyclo[2.2.2]octane bromide (CHF5407), a potent, long-acting, and selective muscarinic M3 receptor antagonist. J Pharmacol Exp Ther. 2010 Dec;335(3):622-35.
Smiles O=C(C1=CC=CS1)C[N+]23C[C@@H](C(CC3)CC2)OC(N(C4=CC(F)=CC=C4)CC5=CC(F)=C(F)C(F)=C5)=O.[Br-]
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Cool pack
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
COVID-19-immunoregulation
Manufacturer - Targets
mAChR
Shipping Temperature
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Molecular Weight
613.46
Product Description
CHF5407 is a selective, long-acting and competitive muscarinic M3 receptor antagonist. CHF5407 shows subnanomolar affinities for human muscarinic M1 (hM1), M2 (hM2) and M3 (hM3) receptors. CHF5407 shows a prolonged antibronchospastic activity[1].
Manufacturer - Research Area
Inflammation/Immunology
Solubility
DMSO: 125 mg/mL (ultrasonic)
Manufacturer - Pathway
GPCR/G Protein; Neuronal Signaling
Isoform
mAChR3
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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