Comparison

Biotinylated Human HLA-A*11:01&B2M&EGFR WT (KITDFGLAK) Monomer Protein (MHC-HE451B)

Item no. MHC-HE451B-100UG
Manufacturer KactusBio
Amount 100 ug
Quantity options 100 ug 500 ug
Category
Format Liquid
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS, Avi
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Dry ice Yes
Sequence Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGLAK peptide
Alias TERT,ILAKFLHWL
Shipping Condition Dry ice
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
HLA-A*02:01&B2M&TERT (ILAKFLHWL)
Manufacturer - Conjugate / Tag
C-His-Avi
Shipping Temperature
Shipped with dry ice.
Storage Conditions
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 35.36 kDa (HLA-A*11:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Description
Recombinant Biotinylated Human HLA-A*11:01&B2M&EGFR WT (KITDFGLAK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGLAK peptide.
Background
The human telomerase catalytic subunit human telomerase reverse transcriptase (hTERT) is expressed in many human cancer cells derived from multiple tissues, but infrequently in normal cells. Thus, hTERT is an attractive candidate target for tumor immunotherapy. hTERT:540–548 peptide (p540, ILAKFLHWL) has been identified as an effective HLA-A*0201-restricted T-cell epitope, an effective T-cell-based cancer treatment, including vaccines, against hTERT will likely require the identification of other MHC class I-restricted epitopes in this antigen.
Endotoxin
Less than 1 EU per μg by the LAL method.
Formulation
Supplied as 0.22 μm filtered solution in 20mM Tris, 200mM NaCl (pH 8.0).
Biotinylated
yes

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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