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(S)-Glutamic acid

(S)-Glutamic acid

Manufacturer	ChemScene
Category	Food Safety Reagents & Chemicals Molecules Amino Acid Analysis
Type	Molecules
Specific against	other
Amount	1000g
Item no.	CS-0003473-1000g
CASRN	56-86-0
eClass 6.1	32169090
eClass 9.0	32169090
Available
Alternative Names	(+)-L-Glutamic acid
CAS	56-86-0
Purity	>98%
MWt	147.13
Formula	C5H9NO4
Solubility	H2O : 6.25 mg/mL (42.48 mM; Need ultrasonic); DMSO : 2 mg/mL (13.59 mM; ultrasonic and warming and heat to 60C)
Clinical Information	Launched
Pathway	Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling; Apoptosis; Metabolic Enzyme/Protease
Target	Apoptosis; iGluR; iGluR; Ferroptosis; Endogenous Metabolite
Biological Activity	(S)-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals. IC50 & Target: DA^[1]. In Vitro: (S)-Glutamic acid (L-glutamic acid) could act on [³H]DA release through presynaptic glutamatergic receptors. L-glutamic acid (50 uM) still stimulated the release of [³H] DA in the presence of tetrodotoxin (0.5 uM)^[1].
Research Area	Neurological Disease

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Delivery expected until 7/4/2024