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NE 10790

NE 10790

Item no.	CS-0006102-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	152831-36-2
Available
Alternative Names	3-PEHPC
CAS	152831-36-2
Purity	>98%
Formula	C8H10NO6P
MWt	247.14
Solubility	H2O : 5 mg/mL (20.23 mM; ultrasonic and adjust pH to 6 with NaOH)
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	NE 10790, a poor farnesyl pyrophosphate synthase inhibitor, is a phosphonocarboxylate analogue of the potent bisphosphonate risedronate and is a weak antiresorptive agent. IC50 & Target: FPP synthase^[1]. In Vitro: NE 10790 inhibits incorporation of [¹⁴C]mevalonic acid into Rab6, but not into H-Ras or Rap1, proteins that are modified by FTase and GGTase I, respectively. NE 10790 reduces viability in J774 cells. NE 10790 prevents prenylation of 22-26-kDa proteins that are not modified by FTase or GGTase I^[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 9/4/2025

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