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Nimustine (hydrochloride)

Nimustine (hydrochloride)

Item no.	CS-0007733-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	55661-38-6
Available
Alternative Names	ACNU
CAS	55661-38-6
Purity	>98%
Formula	C9H14Cl2N6O2
MWt	309.15
Solubility	DMSO : 62.5 mg/mL (202.17 mM; Need ultrasonic)
Clinical Information	Phase 2
Pathway	Apoptosis; Cell Cycle/DNA Damage
Target	Apoptosis; DNA/RNA Synthesis
Biological Activity	Nimustine hydrochloride (ACNU) is a DNA cross-linking and DNA alkylating agent, which induces DNA replication blocking lesions and DNA double-strand breaks and inhibits DNA synthesis, commonly used in chemotherapy for glioblastomas^[1]^[2]^[3].

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Amount: 50mg

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