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Tpl2 Kinase Inhibitor 1

Tpl2 Kinase Inhibitor 1

Item no.	CS-0011091-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Oncology By Cell Type Melanoma Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	871307-18-5
Similar products	871307-18-5
Available
CAS	871307-18-5
Purity	>98%
MWt	404.83
Formula	C21H14ClFN6
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	MAPK/ERK Pathway
Target	MAP3K
Biological Activity	Tpl2 Kinase Inhibitor 1 (Compound 1) is a potent and selective Tpl2 (COT kinase, MAP3K8) inhibitor, plays an important role in the regulation of the inflammatory response and the progression of some cancers^[1]. IC50 & Target: Tpl2/COT kinase/MAP3K8^[1] In Vitro: Cancer Osaka thyroid (COT) kinase (Tpl2) is an important regulator of pro-inflammatory cytokines in macrophages^[1].
Research Area	Cancer; Inflammation/Immunology

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 10/2/2025

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