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RIPK1-IN-4

RIPK1-IN-4

Item no.	CS-0014575-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Cell Biology Cell Status Apoptosis Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1481641-08-0
Similar products	1481641-08-0
Available
CAS	1481641-08-0
Purity	>98%
MWt	401.46
Formula	C23H23N5O2
Solubility	DMSO : 250 mg/mL (622.73 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Apoptosis
Target	RIP kinase
Biological Activity	RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC₅₀s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase^[1]. IC50 & Target: IC50: 16 nM (RIP1) and 10 nM (ADP-Glo)^[1]
Research Area	Inflammation/Immunology

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Amount: 10mg

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Delivery expected until 10/2/2025

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