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m-3M3FBS

m-3M3FBS

Item no.	CS-0015976-5mg
Manufacturer	ChemScene
CASRN	200933-14-8
Amount	5mg
Category	Cardiovascular Research Thrombosis & Hemostasis Atherosclerosis Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	200933-14-8
Similar products	200933-14-8
Available
CAS	200933-14-8
Purity	>98%
MWt	343.36
Formula	C16H16F3NO2S
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Apoptosis; Metabolic Enzyme/Protease
Target	Apoptosis; Phospholipase
Biological Activity	m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis^[1]^[2]^[3]. In Vitro: m-3M3FBS (5-50 uM) stimulates the formation of inositol phosphates in U937 cells^[1]. m-3M3FBS (50 uM; 24 hours) inhibits the growth of the leukemic cell lines U937 and THP-1, but not primary monocytes^[3]. m-3M3FBS (50 uM; 24 hours) induces U937 cell apoptosis^[3].
Research Area	Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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