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Rho-Kinase-IN-1

Rho-Kinase-IN-1

Item no.	CS-0018421-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Cardiovascular Research Hypertension Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1035094-83-7
Similar products	1035094-83-7
Available
CAS	1035094-83-7
Purity	>98%
MWt	352.50
Formula	C20H24N4S
Solubility	DMSO : 50 mg/mL (141.84 mM; ultrasonic and warming and heat to 60C)
Clinical Information	No Development Reported
Pathway	TGF-beta/Smad; Stem Cell/Wnt; Cell Cycle/DNA Damage; Cytoskeleton
Target	ROCK; ROCK; ROCK; ROCK
Biological Activity	Rho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor (K_i values of 30.5 and 3.9 nM for ROCK1 and ROCK2, respectively) extracted from US20090325960A1, compound 1.008^[1]. IC50 & Target: Ki: 30.5 nM (ROCK1), 3.9 nM (ROCK2)^[1] In Vitro: Rho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases or conditions associated with excessive cell proliferation, remodeling, edema and inflammation^[1].
Research Area	Cancer

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100mg

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Delivery expected until 10/2/2025

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