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NH2-PEG2-C2-Boc

NH2-PEG2-C2-Boc

Item no.	CS-0020723-25g
Manufacturer	ChemScene
Amount	25g
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	756525-95-8
Similar products	756525-95-8
Available
CAS	756525-95-8
Purity	>98%
MWt	233.30
Formula	C11H23NO4
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Antibody-drug Conjugate/ADC Related; PROTAC
Target	ADC Linker; PROTAC Linker
Biological Activity	NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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