YM-750

Item no.	CS-0028367-5mg
Manufacturer	ChemScene
CASRN	138046-43-2
Amount	5mg
Category	Cardiovascular Research Atherosclerosis Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	138046-43-2
Similar products	138046-43-2
Available
CAS	138046-43-2
Purity	>98%
MWt	452.63
Formula	C31H36N2O
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	Acyltransferase
Biological Activity	YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC₅₀=0.18 uM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A^[1]^[2]. In Vitro: Foam cells accumulated esterified cholesterol (EC) for 24 h in the presence of acLDL without Cu²⁺, which is suppressed by KY-455 and YM-750^[3].
Research Area	Cardiovascular Disease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5mg

available

Delivery expected until 10/2/2025

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer