IM-54

Item no.	CS-0028433-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	861891-50-1
Similar products	861891-50-1
Available
CAS	861891-50-1
Purity	>98%
MWt	325.40
Formula	C19H23N3O2
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activities against H₂O₂-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tools for investigating the molecular mechanisms of cell death^[1]^[2]. In Vitro: IM-54 is found to selectively inhibit oxidative stress-induced necrosis, but it does not inhibit apoptosis induced by various anticancer drugs or Fas ligand, or necroptosis^[1]. IM-54 shows strong inhibition of H₂O₂-induced necrosis, with an IC₅₀ of 0.25 uM against HL-60 cells treated with H₂O₂^[1].
Research Area	Cardiovascular Disease

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