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AY 9944

AY 9944

Item no.	CS-0028448-50mg
Manufacturer	ChemScene
CASRN	366-93-8
Amount	50mg
Category	Cardiovascular Research Atherosclerosis Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	366-93-8
Similar products	366-93-8
Available
CAS	366-93-8
Purity	>98%
MWt	464.30
Formula	C22H30Cl4N2
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol delta7-reductase (DHCR7) enzyme (IC50=13 nM). AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol delta7-delta8 isomerase, which causes the accumulation of cholest-8-en-3beta-ol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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