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Angiotensin II (3-8), human (TFA)

Angiotensin II (3-8), human (TFA)

Item no.	CS-0058438-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Cardiovascular Research Heart Failure Myocardial Infarction Hypertension Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Purity	>98%
Formula	C42H55F3N8O10
MWt	888.93
Solubility	H2O : 50 mg/mL (56.25 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	GPCR/G Protein
Target	Angiotensin Receptor
Biological Activity	Angiotensin II (3-8), human (TFA) is a less effective agonist at the angiotensin AT₁ receptor. IC50 & Target: Angiotensin AT₁ receptor^[1]. In Vivo: Human Angiotensin II (3-8) causes endothelium-dependent renal cortical vasodilatation, in anaesthetized rats. At doses up to 125 pmol/kg, human Angiotensin II (3-8) is without any cardiovascular effects, but with doses of 1.25 and 12.5 nmol/kg there are dose-dependent increases in mean arterial blood pressure and reductions in renal and mesenteric flows and vascular conductances^[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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