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SHIP2-IN-1

SHIP2-IN-1

Item no.	CS-0062822-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Oncology Metabolism Glucose Homeostasis By Cell Type Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2252247-80-4
Similar products	2252247-80-4
Available
CAS	2252247-80-4
Purity	>98%
MWt	379.22
Formula	C17H13Cl2FN4O
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	Phosphatase
Biological Activity	SHIP2-IN-1 is a potent SHIP2 inhibitor, inhibits SHIP2 activity, with an IC₅₀ of 2 uM. SHIP2-IN-1 blocks GSK3beta activation by phosphorylation at the Ser9 residue. SHIP2-IN-1 is used in the research of Alzheimer's disease^[1]. IC50 & Target: IC50: 2 uM (SHIP2)^[1] In Vitro: SHIP2-IN-1 (Compound 43; 10 uM) significantly inhibits PI(3, 4)P2 production in HT22 cells^[1].
Research Area	Neurological Disease

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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Delivery expected until 10/2/2025

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