SMAP-2

Item no.	CS-0077430-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Oncology Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences Neural Signaling By Cell Type Blastoma Reagents & Chemicals Molecules Astrocyte Markers
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1809068-70-9
Similar products	1809068-70-9
Available
Alternative Names	DT-1154
CAS	1809068-70-9
Purity	>98%
MWt	532.57
Formula	C27H27F3N2O4S
Solubility	DMSO : 300 mg/mL (563.31 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	Phosphatase
Biological Activity	SMAP-2 (DT-1154) is an orally bioavailable phosphatase 2A (PP2A) activator which binds to the PP2A Aalpha scaffold subunit to drive conformational changes in PP2A. SMAP-2 (DT-1154) inhibits the growth of KRAS-mutant lung cancers ^[1]. IC50 & Target: PP2A^[1]
Research Area	Cancer

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Amount: 10mg

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Delivery expected until 10/2/2025

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