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IRAK4-IN-4

IRAK4-IN-4

Item no.	CS-0078778-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1850276-58-2
Similar products	1850276-58-2
Available
CAS	1850276-58-2
Purity	>98%
MWt	340.37
Formula	C22H16N2O2
Solubility	DMSO : 25 mg/mL (73.45 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Immunology/Inflammation; Immunology/Inflammation
Target	IRAK; Cyclic GMP-AMP Synthase
Biological Activity	IRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC₅₀ of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC₅₀ of 2.1 nM^[1]. IC50 & Target: IC50: 2.8 nM (IRAK4), 2.1 nM (cGAS)^[1]
Research Area	Inflammation/Immunology

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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Delivery expected until 9/4/2025

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