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JND3229

JND3229

Item no.	CS-0078820-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2260886-64-2
Similar products	2260886-64-2
Available
CAS	2260886-64-2
Purity	>98%
MWt	617.18
Formula	C33H41ClN8O2
Solubility	DMSO : 100 mg/mL (162.03 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Target	EGFR; EGFR
Biological Activity	JND3229 is a highly potent and fourth-generation EGFR^C797S reversible inhibitor with IC₅₀ value of 5.8 nM, and also potently suppressed EGFR^L858R/T790M and EGFR^WT with IC₅₀ values of 30.5 and 6.8 nM.
Research Area	Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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Delivery expected until 9/4/2025

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