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Carebastine

Carebastine

Item no.	CS-0081566-1mg
Manufacturer	ChemScene
Amount	1mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	90729-42-3
Similar products	90729-42-3
Available
CAS	90729-42-3
Purity	>98%
MWt	499.64
Formula	C32H37NO4
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Immunology/Inflammation; GPCR/G Protein; Neuronal Signaling
Target	Histamine Receptor; Histamine Receptor; Histamine Receptor
Biological Activity	Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner^[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor^[2]. IC50 & Target: Histamine H1 receptor^[1]
Research Area	Cancer; Endocrinology

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