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Dynarrestin

Dynarrestin

Item no.	CS-0083323-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2222768-84-3
Similar products	2222768-84-3
Available
CAS	2222768-84-3
Purity	>98%
MWt	431.50
Formula	C22H23F2N3O2S
Solubility	DMSO : 83.33 mg/mL (193.12 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Stem Cell/Wnt
Target	Hedgehog
Biological Activity	Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin rapidly and reversibly inhibits dynein 1-driven microtubule gliding in vitro plus a range of dynein 1- and 2-dependent processes in cells without affecting ATP hydrolysis and interfering with ciliogenesis. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells^[1].
Research Area	Cancer

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