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Mutant IDH1-IN-4

Mutant IDH1-IN-4

Item no.	CS-0086053-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	1416270-18-2
Available
CAS	1416270-18-2
Purity	>98%
Formula	C25H34N4O3
MWt	438.56
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	Isocitrate Dehydrogenase (IDH)
Biological Activity	Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC₅₀ values of <= 0.5 uM for mutant IDH1 in R132H, HT1080 and U87R132H cells^[1]. IC50 & Target: IC50: <= 0.5 uM (mutant IDH 1 in cells)^[1].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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