M1001

Item no.	CS-0087092-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	874590-32-6
Similar products	874590-32-6
Available
CAS	874590-32-6
Purity	>98%
MWt	327.40
Formula	C17H17N3O2S
Solubility	DMSO : 250 mg/mL (763.59 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	HIF/HIF Prolyl-Hydroxylase
Biological Activity	M1001 is a weak agonist of HIF-2alpha, directly binds to the HIF-2alpha PAS-B domain, with a K_d of 667 nM. M1001 enhances the stabilities of HIF-2alpha-ARNT complex^[1]. IC50 & Target: Kd: 667 nM (HIF-2alpha)^[1]
Research Area	Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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