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HSP27 inhibitor J2

HSP27 inhibitor J2

Item no.	CS-0087244-25mg
Manufacturer	ChemScene
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2133499-85-9
Similar products	2133499-85-9
Available
Alternative Names	J2
CAS	2133499-85-9
Purity	>98%
MWt	264.30
Formula	C13H12O4S
Solubility	DMSO : 25 mg/mL (94.59 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease; Cell Cycle/DNA Damage
Target	HSP; HSP
Biological Activity	HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition^[1]^[2]. IC50 & Target: HSP27^[2]
Research Area	Cancer

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Amount: 25mg

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Delivery expected until 7/3/2025

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