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p32 Inhibitor M36

p32 Inhibitor M36

Item no.	CS-0087411-25mg
Manufacturer	ChemScene
Amount	25mg
Category	Oncology By Cell Type Hematology Leukemia Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	802555-85-7
Similar products	802555-85-7
Available
Alternative Names	M36
CAS	802555-85-7
Purity	>98%
MWt	448.52
Formula	C23H28N8O2
Solubility	DMSO : 5 mg/mL (11.15 mM; ultrasonic and warming and heat to 80C)
Clinical Information	No Development Reported
Pathway	TGF-beta/Smad; Epigenetics
Target	PKC; PKC
Biological Activity	p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1^[1]. IC50 & Target: p32^[1] In Vitro: p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC₅₀ of 77.9 uM in complete media) and is much more potent under low glucose conditions with an IC₅₀ of 7.3 uM^[1]. p32 Inhibitor M36 is selective for p32 overexpressing cells^[1]. p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC₅₀ of 2.8 uM^[1].
Research Area	Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 10/2/2025

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