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(R)-BAY1238097

(R)-BAY1238097

Item no.	CS-0089882-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	1564269-85-7
Available
CAS	1564269-85-7
Purity	>98%
Formula	C25H33N5O3
MWt	451.56
Solubility	H2O : < 0.1 mg/mL (insoluble); DMSO : 150 mg/mL (332.18 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Epigenetics
Target	Epigenetic Reader Domain
Biological Activity	(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome^[1]^[2]. IC50 & Target: BET^[1].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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