Comparison

Thalidomide-PEG2-C2-NH2 (TFA)

Item no. CS-0112179-1mg
Manufacturer ChemScene
Amount 1mg
Category
Type Molecules
Specific against other
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias 2097509-36-7
Similar products 2097509-36-7
Available
Alternative Names
Thalidomide-NH-PEG2-C2-NH2 (TFA)
CAS
2097509-36-7
Purity
>98%
MWt
518.44
Formula
C21H25F3N4O8
Solubility
10 mM in DMSO
Clinical Information
No Development Reported
Pathway
PROTAC
Target
E3 Ligase Ligand-Linker Conjugate
Biological Activity
Thalidomide-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Research Area
Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
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