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Sparfosic acid (trisodium)

Sparfosic acid (trisodium)

Item no.	CS-0114053-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	70962-66-2
Similar products	70962-66-2
Available
CAS	70962-66-2
Purity	>98%
MWt	321.06
Formula	C6H7NNa3O8P
Solubility	H2O : 250 mg/mL (778.67 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	Sparfosic acid trisodium, is a potent inhibitor of aspartate transcarbamoyl transferase, with anti-tumor and antimetabolite activity. Aspartate transcarbamoyl transferase catalyzes the second step of de novo pyrimidine biosynthesis^[1]^[2]. In Vitro: Sparfosic acid (PALA) treatment causes apoptosis in the resistant Br1 cells^[1]. Sparfosic acid (PALA, 300 uM) shows progressive accumulation of cells in S phase and activation of an apoptotic pathway leading to cell death^[1].
Research Area	Cancer; Metabolic Disease

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Amount: 10mg

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