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Tos-PEG4-THP

Tos-PEG4-THP

Item no.	CS-0114255-1g
Manufacturer	ChemScene
Amount	1g
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	86259-89-4
Similar products	86259-89-4
Available
CAS	86259-89-4
Purity	>98%
MWt	432.53
Formula	C20H32O8S
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	PROTAC
Target	PROTAC Linker
Biological Activity	Tos-PEG4-THP is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523)^[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Research Area	Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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