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Biotin-PEG4-alkyne

Biotin-PEG4-alkyne

Item no.	CS-0114530-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1458576-00-5
Similar products	1458576-00-5
Available
CAS	1458576-00-5
Purity	>98%
MWt	457.58
Formula	C21H35N3O6S
Solubility	DMSO : 100 mg/mL (218.54 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	PROTAC
Target	PROTAC Linker
Biological Activity	Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].
Research Area	Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

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