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AZD2423

AZD2423

Item no.	CS-0116098-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1229603-37-5
Similar products	1229603-37-5
Available
CAS	1229603-37-5
Purity	>98%
MWt	425.93
Formula	C20H29ClFN5O2
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Immunology/Inflammation; GPCR/G Protein
Target	CCR; CCR
Biological Activity	AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator. AZD2423 has an IC₅₀ of 1.2 nM for CCR2 Ca²⁺ flux ^[1]^[2]^[3]. In Vitro: AZD2423 inhibits MCP-1 induced calcium mobilization and chemotaxis of THP-1 cell line with an IC₅₀ of 4 nM^[1].
Research Area	Neurological Disease

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 1/1/2026

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