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3,4-Dehydro Cilostazol

3,4-Dehydro Cilostazol

Item no.	CS-0116250-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	73963-62-9
Similar products	73963-62-9
Available
Alternative Names	OPC-13015
CAS	73963-62-9
Purity	>98%
MWt	367.44
Formula	C20H25N5O2
Solubility	DMSO : 5 mg/mL (13.61 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	Drug Metabolite
Biological Activity	3, 4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3, 4-Dehydro Cilostazol is used for pharmacokinetic study^[1]. In Vivo: 3, 4-Dehydro Cilostazol (OPC-13015; Oral; 1 mg/kg GLZ and 10 mg/kg CLZ) has a T_1/2 of 3.94 hours, a C_max of 1.39 uM and an AUC_0-24 of 4.69 ug-h/ml. The plasma concentration time profiles of GLZ, CLZ & its active metabolite DCLZ are traceable up to 24 h, 12 h and 12 h respectively by oral administration at 1 mg/kg dose of GLZ and 10 mg/kg CLZ^[1].
Research Area	Cancer; Cardiovascular Disease

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