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EED226-COOH

EED226-COOH

Item no.	CS-0119640-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2467965-71-3
Similar products	2467965-71-3
Available
CAS	2467965-71-3
Purity	>98%
MWt	335.32
Formula	C17H13N5O3
Solubility	DMSO : 125 mg/mL (372.78 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	PROTAC
Target	Ligand for Target Protein for PROTAC
Biological Activity	EED226-COOH is an EED226-derived ligand for target protein EED ligand for PROTAC, binds to a ligand for VHL via linker to form UNC6852 (HY-130708) to degrade PRC2^[1]. IC50 & Target: EED^[1] In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Research Area	Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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